Importance of Ara h 6 in peanut allergy diagnosis
نویسندگان
چکیده
منابع مشابه
Importance of Ara h 6 in peanut allergy diagnosis
Results Twenty-two children (median age: 6.63 y.o.; IQR: 5.22-10.12) were classified as allergic in the basis of at least two convincing clinical reactions upon ingestion of PNT in the last two years. Sixty-nine children (median age: 8.01 y.o.; IQR: 6.01-11.27) were classified as tolerant on the basis of regular consumption of PNT. Positive SPT with commercial PNT extract was found in 86% of th...
متن کاملAra h 6 sensitization in peanut allergy: friend, foe or innocent bystander?
The clinical role of Ara h 6 sensitization in peanut allergy is a current matter of debate. We investigated the role of Ara h 6 sensitization patterns in a sample of young adults from different Italian cities. Sera of 33 patients with specific IgE against Ara h 6 were selected. According to clinical symptoms upon peanut ingestion, patients were divided into severe reaction (SR) and mild-toleran...
متن کاملThe individual role of peanut proteins Ara h1, 2, 3 and 6 in peanut allergy
One of the major allergenic food or food constituent is peanut, in which a number of allergenic proteins have been described (Ara h1-9). Until now, the relative contribution of the individual peanut allergens to clinical food allergic responses is not known. Therefore, the present studies aimed to elucidate the relative contribution of Ara h1, 2, 3, and 6 to peanut allergy in a mouse model. For...
متن کاملAra h 6 complements Ara h 2 as an important marker for IgE reactivity to peanut
The similarities of two major peanut allergens, Ara h 2 and Ara h 6, in molecular size, amino acid sequence, and structure have made it difficult to obtain natural Ara h 6 free of Ara h 2. The objectives of this study were to purify natural Ara h 6 that is essentially free of Ara h 2 and to compare its IgE reactivity and potency in histamine release assays to Ara h 2. Sodium dodecyl sulfate-pol...
متن کاملDiagnostic Value of Specific IgE to Peanut and Ara h 2 in Korean Children with Peanut Allergy
PURPOSE The purpose of this study was to establish the diagnostic decision point (DDP) of peanut specific IgE (sIgE) for predicting the outcome of oral food challenge (OFC). We also evaluated the usefulness of sIgE to peanut components (Ara h 1, 2, 3, 8, and 9) in diagnosing peanut allergy. METHODS Korean children aged over 12 months with a suspected peanut allergy were enrolled. Diagnosis of...
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ژورنال
عنوان ژورنال: Clinical and Translational Allergy
سال: 2014
ISSN: 2045-7022
DOI: 10.1186/2045-7022-4-s2-o16